SBS 2011 – Exchange 2010 Sending email issue – 451 421 - Emails stuck in outbound queue

 

SBS 2011 – Exchange 2010 Sending email issue – 451 421

Emails Stuck in the outbound queue with the 451 error

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After a LOT of searching for this answer – two came alone together!

451 4.4.0 primary target ip address responded with 421 4.2.1 unable to connect. Attempted failover to alternate host, but that did not succeed. Either there are no alternative hosts, or the delivery failed to all alternate hosts

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